Comparative Review of the Current and Future Strategies to Evaluate Bone Marrow Infiltration at Diffuse Large B-Cell Lymphoma Diagnosis.

Diffuse large B-cell lymphoma (DLBCL) requires a complete staging at diagnosis that may have prognostic and therapeutic implications. The role of bone marrow (BM) biopsy (BMB) is controversial in the era of nuclear imaging techniques. We performed a comparative review of 25 studies focused on BM evaluation at DLBCL diagnosis, including at least two of the following techniques: BMB, flow cytometry, and positron emission tomography (PET-FDG).

Immune response in breast cancer surgery. A comparative and prospective study of different anesthetic techniques.

Introduction: The main reason for high mortality in breast cancer is local recurrence and metastasis, despite surgery as the first therapeutic option. The anesthesia used in the operation room can determine the immune response.

Methods: A prospective, comparative and non- randomised study in patients undergoing breast cancer surgery was conducted in our hospital after obtaining approval from the Hospital's Institutional Review Board.

TRBC1 expression assessed by flow cytometry as a novel marker of clonality in cutaneous αβ T-cell lymphomas with peripheral blood involvement.

The TRBC1 evaluation is a useful, simple, and fast flow cytometry tool for the assessment of αβ T-cell clonality in the blood of patients suspicious of mycosis fungoides and Sézary syndrome.