Publications by authors named "J Garcia-Reyero"

Plasmablastic lymphoma mutational profile is undescribed. Here we performed a targeted exonic NGS analysis of 30 plasmablastic lymphoma cases with a B cell lymphoma dedicated panel and FISH for the detection of MYC rearrangements. A complete phenotyping of the neoplastic and microenvironment cell populations was also performed.

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Article Synopsis
  • * Researchers reviewed 35 bone marrow biopsies from 28 patients, employing various methods such as morphology analysis, immunohistochemistry, and next-generation sequencing (NGS) to find mutations related to lymphoma.
  • * Results indicated that bone marrow trephine biopsy is more effective than flow cytometry for detecting lymphoid infiltrates, with specific infiltration patterns observed in LPL/WM and IgM-MGUS cases; mutations other than p.L265P were also identified in a subset of cases.
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