Publications by authors named "J Garavaglia"
Context: Olive leaf extract (OLE) is rich in phenolic compounds, which are known for their health benefits. Cardiovascular diseases, primarily coronary heart disease and stroke, are leading causes of mortality globally.
Objective: This systematic review aimed to assess the impact of OLE on cardiometabolic risk factors in adults.
Background And Objectives: Intrathecal (IT) medications are routinely introduced through catheterization of the intraventricular space or subarachnoid space. There has been sporadic use of IT medications delivered directly to the ventricle either by intermittent injection through an external ventricular drain (EVD) or by an Ommaya reservoir with a ventricular catheter. IT medication delivery through EVD has many drawbacks, including the necessary opening of a sterile system, delivery of medication in a bolus form, and requirements to clamp the EVD after medication delivery.
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- - Study investigates the effectiveness of peripheral nerve blocks (PNBs) as a treatment for headache after an aneurysmal subarachnoid hemorrhage (HASH), comparing it to standard medication treatments.
- - In a pilot study of 10 patients (5 in control, 5 receiving PNBs), the PNB group showed a significant reduction in pain scores immediately after treatment compared to the control group.
- - Results indicate that PNBs may be a safe and effective option for alleviating HASH pain, suggesting that larger studies are needed to confirm these findings.
Tocilizumab and baricitinib have emerged as potential treatments for patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) following the findings of the Recovery Group and the results of the COV-BARRIER study. Unfortunately, there is a lack of guidance regarding the use of these agents in high-risk patients, such as those with obesity. To compare the outcomes of tocilizumab and baricitinib as potential treatments for obese patients infected with SARS-CoV-2.
View Article and Find Full Text PDFOleuropein is a polyphenol found in olive trees that has shown beneficial effects in animal studies and potentially in human health, although few studies have been performed to confirm this hypothesis in the latter population. Previous studies related its antioxidant activity to cardioprotective effects and showed a positive correlation between dose and response. We thus aimed to assess the cardioprotective effect of oleuropein and olive leaf extract in animal experiments.
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