Management of Pregabalin Use Disorder: A Case Series.

Pregabalin is indicated for the treatment of partial epilepsy, generalized anxiety disorder, and neuropathic pain. The first reports on pregabalin use disorder have been published in Europe in 2010 and notified to the French Addictovigilance Network (FAN) in 2011. The management of pregabalin use disorder is challenging due to the risks associated with the abrupt withdrawal and lack of guidelines.

Taste sensitivity of detritivorous mosquito larvae to decomposed leaf litter.

Dietary leaf litter chemistry is known to play an important ecotoxicological role in the plant-mosquito interaction in subalpine flooded areas surrounded by vegetation because of differential larvicidal effects of insoluble polyphenols formed during the leaf decaying process. This dietary interaction was investigated through comparative evaluation of the role of toxic/nontoxic leaf litter in both larval foraging and feeding behavior, by using different samples of decomposed alder leaf litter and larval Aedes aegypri as experimental references. Track analysis showed significant differences in larval foraging behavior in the absence or presence of leaf litter.

Locomotory behavior of flightless Harmonia axyridis Pallas (Col., Coccinellidae).

To improve the efficiency of the ladybeetle Harmonia axyridis as a biological control agent against aphids, a flightless population was produced by feeding adults with a mutagen and selecting their progeny for non-flying but otherwise morphologically normal individuals. The inability to fly could result from a change in their flying behavior compared with control adults. Flight duration was very much shorter, wing beat frequency and more particularly the amplitude of the wing beats were clearly lower.