Publications by authors named "J Gager"
A catalogue of neuronal cell types has often been called a 'parts list' of the brain, and regarded as a prerequisite for understanding brain function. In the optic lobe of Drosophila, rules of connectivity between cell types have already proven to be essential for understanding fly vision. Here we analyse the fly connectome to complete the list of cell types intrinsic to the optic lobe, as well as the rules governing their connectivity.
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- Researchers have created a detailed neuronal wiring diagram of the whole brain of a fruit fly (Drosophila melanogaster), mapping over 5 billion chemical synapses between more than 139,000 neurons, to better understand brain function.
- The study includes detailed annotations about various cell types, nerve pathways, and neurotransmitter identities, and the data is freely available for other researchers to use and explore.
- By analyzing synaptic pathways and connections, the project helps illustrate how neural structures relate to sensorimotor behaviors, paving the way for similar studies in other species.
Article Synopsis
- Animal movement is directed by motor neurons that connect the central nervous system to muscles, with complex premotor networks coordinating these movements for various behaviors.
- Researchers analyzed the wiring of premotor circuits in Drosophila flies to understand how motor networks control leg and wing movements.
- They discovered that leg motor modules have a hierarchical structure based on the size of motor neurons, while wing circuits are more flexible in their connectivity, highlighting differences in motor control for distinct body parts.
Article Synopsis
- This study focuses on understanding how neural circuits in the brain manage behavior by analyzing the Drosophila melanogaster (fruit fly) ventral nerve cord, which mirrors the spinal cord in vertebrates.
- Researchers mapped approximately 45 million synapses and 14,600 neuron cell bodies within the fruit fly's nerve cord to comprehend its neural connections.
- They created a motor neuron atlas that identifies which muscles are targeted by motor neurons, aiding in the understanding of leg and wing movement coordination, especially during take-off.
A catalog of neuronal cell types has often been called a "parts list" of the brain, and regarded as a prerequisite for understanding brain function. In the optic lobe of , rules of connectivity between cell types have already proven essential for understanding fly vision. Here we analyze the fly connectome to complete the list of cell types intrinsic to the optic lobe, as well as the rules governing their connectivity.
View Article and Find Full Text PDF