Publications by authors named "J GODART"
Article Synopsis
- - The study aimed to identify errors in transrectal ultrasound (TRUS)-based reconstructions for high-dose-rate brachytherapy in prostate cancer, using an electromagnetic tracking (EMT) system to enhance accuracy during treatment.
- - Out of 265 evaluated needle reconstructions, 23% had minor errors or worse, with 9% classified as major or severe, primarily due to issues like incorrect needle placement and user errors.
- - The findings indicate that one-quarter of the reconstructions had errors exceeding 2mm, highlighting the potential of EMT to help detect and prevent these mistakes, improving patient care without affecting the clinical process.
This study aims to determine a margin and robustness setting for treating locally advanced cervical cancer (LACC) with a library-of-plans (LoP) based online-adaptive intensity-modulated proton therapy (IMPT).We analyzed 13 LACC patients with delineated planning and weekly repeat CT scans (reCTs). For each patient, 120 IMPT treatments of 25 fractions were simulated with a LoPs approach.
View Article and Find Full Text PDFBackground: Pre-clinical studies demonstrate that delivering a high dose at a high dose rate result in less toxicity while maintaining tumor control, known as the FLASH effect. In proton therapy, clinical trials have started using 250 MeV transmission beams and more trials are foreseen. A novel aspect of FLASH treatments, compared to conventional radiotherapy, is the importance of dose rate next to dose and geometry.
View Article and Find Full Text PDFBackground And Purpose: To investigate the trade-off between bone marrow sparing (BMS) and dose to organs at risk (OARs) for intensity modulated proton therapy (IMPT) for women with locally advanced cervical cancer (LACC).
Materials And Methods: Twenty LACC patients were retrospectively included. IMPT plans were created for each patient using automated treatment planning.
Objective: To investigate the potential of hybrid Pd/Fe-oxide magnetic nanoparticles designed for thermo-brachytherapy of breast cancer, considering their specific loss power () and clinical constraints in the applied magnetic field.
Methods: Hybrid nanoparticles consisting of palladium-core and iron oxide shell of increasing thickness, were suspended in water and their were measured at varying magnetic fields (12-26 mT peak) and frequencies (50-730 kHz) with a commercial alternating magnetic field generator (magneTherm™ Digital, nanoTherics Ltd.).