Publications by authors named "J G van den Broek"

In high-producing dairy cows periparturient negative energy balance (NEB) triggers body fat mobilization, resulting in elevated blood levels of non-esterified fatty acids (NEFAs). Blood is dominated by the saturated fatty acids (SFA) palmitic (C16:0) and stearic acid (C18:0), which are associated with a negative effect on oocyte developmental competence. In contrast, the monounsaturated fatty acid (MUFA) oleic acid is harmless and is able to counteract the negative effect of saturated NEFAs on in vitro maturing oocytes.

View Article and Find Full Text PDF

Background: Alopecia X (AX) is a common noninflammatory alopecic condition of Pomeranian dogs with an unknown cause. While a genetic aetiology is suspected, no current tests can predict the development of this disorder or confirm the aetiology. Therefore, identifying potential risk indicators for the development of AX would be of value in this breed.

View Article and Find Full Text PDF

Equine herpesvirus 1 (EHV-1) infection is the cause of high impact disease syndromes, affecting the global horse industry. The effect of vaccination on transmission dynamics of EHV-1 in naturally occurring outbreaks is not quantified. Our aims were to estimate R for EHV-1 in equine populations from outbreak data, and evaluate the effect of vaccination status of the herd on R through a systematic review, model-based estimations and meta-analysis.

View Article and Find Full Text PDF

Background: Survivorship care plans (SCPs), ie, personalized health care plans for cancer survivors, can be used to support the growing group of melanoma survivors throughout their disease trajectory. However, implementation and effectiveness of SCPs are suboptimal and could benefit from the involvement of stakeholders in developing a user-centered design.

Objective: The aim of this study was to identify the ideal SCP for patients with melanoma in terms of functions and features to be included according to different stakeholders and to explore their underlying motives.

View Article and Find Full Text PDF

Both the development and progression of atrial fibrillation (AF) are affected by a range of modifiable lifestyle risk factors. These key modifiable risk factors encompass obesity, hypertension, hypercholesterolemia, diabetes mellitus, smoking, chronic obstructive pulmonary disease, alcohol consumption, exercise, sedentary lifestyle and obstructive sleep apnoea. These lifestyle-dependent factors rarely exist in isolation, but rather exist together, exerting a complex influence on the development of AF.

View Article and Find Full Text PDF