Publications by authors named "J G Santillan-Benitez"
Article Synopsis
- - The study investigates how pollutants from untreated hospital effluents, particularly heavy metals and pharmaceuticals, harm aquatic ecosystems, specifically focusing on their toxic effects on zebrafish embryos (Danio rerio).
- - Researchers quantified various pharmaceutical residues and heavy metals, finding significant embryolethal potential and various malformations in zebrafish embryos exposed to different concentrations of effluent over time.
- - Findings showed increased oxidative stress, lipid and protein damage, and altered gene expression linked to antioxidant defense and apoptosis, underscoring the urgent need for effective hospital effluent treatment to protect water quality and ecosystem health.
(1) Background: Could compounds such as monoterpenes and sesquiterpenes present in essential plant oils inhibit bacterial growth as an alternative to help mitigate bacterial resistance? The purpose of this study is evaluating the in vitro antibacterial effect of EO (LEO) and EO (TEO), individually and in combination with ampicillin, against extended-spectrum beta-lactamase (ESBL)-producing strains; (2) Methods: Experimental in vitro design with post-test. The EOs were obtained by hydrodistillation and were analyzed by GC. ESBL-producing strains used were selected from urine cultures and the and resistance genes were identified by end point PCR.
View Article and Find Full Text PDFIt has been proposed that infection by adipogenic viruses constitutes a "low risk" factor for obesity. Here, we report the presence of adenovirus 36 (Ad36) and its viral load copy number in fat tissue of participants with obesity and normal weight; phylogenetic analysis was performed to describe their relationship and genetic variability among viral haplotypes. Adipose tissue obtained from 105 adult patients with obesity (cases) and 26 normal-weight adult participants as controls were analyzed by quantitative polymerase chain reaction (qPCR) amplifying the partial Ad36 E1a gene.
View Article and Find Full Text PDFHuman Adenovirus 36 (HAdV-36) has been related to diverse effects on metabolism and may attenuate the lipid accumulation in kidneys with increased adiposity. Some of these effects would be related to viral persistence. However, until now, a model of persistent in vitro infection by HAdV-36 is unknown.
View Article and Find Full Text PDFAlthough liposomal doxorubicin (LPD) is widely used for cancer treatment, knowledge concerning the toxicity induced by this drug in healthy organs and tissues is limited. LPD-induced toxicity studies relative to free doxorubicin (DOX) have focused on cardiotoxicity in tumor-bearing animals. On the other hand, the results on DOX-induced cardiotoxicity depending on gender are controversial.
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