Impact of Heterogeneous Plaque Deposition on Computed Tomography Derived Fractional Flow Reserve.

L/P ratio, which indicates the proportion of lumen volume to plaque volume of the vessel, is lower in lesion than in per-lesion (RCA, 0.9 vs. 7.

Investigating patellar motion using weight-bearing dynamic CT: normative values and morphological considerations for healthy volunteers.

Background: Patellar instability is a well-known pathology in which kinematics can be investigated using metrics such as tibial tuberosity tracheal groove (TTTG), the bisect offset (BO), and the lateral patellar tilt (LPT). We used dynamic computed tomography (CT) to investigate the patellar motion of healthy subjects in weight-bearing conditions to provide normative values for TTTG, BO, and LPT, as well as to define whether BO and LPT are affected by the morphology of the trochlear groove.

Methods: Dynamic scanning was used to acquire images during weight-bearing in 21 adult healthy volunteers.

Emerging Roles of Bile Acids and TGR5 in the Central Nervous System: Molecular Functions and Therapeutic Implications.

Bile acids (BAs) are cholesterol derivatives synthesized in the liver and released into the digestive tract to facilitate lipid uptake during the digestion process. Most of these BAs are reabsorbed and recycled back to the liver. Some of these BAs progress to other tissues through the bloodstream.