A qualitative exploration of the views of paramedics regarding the use of dark humour.

Introduction: Dark humour, often known as black comedy or gallows humour, is a distinct kind of humour that explores subjects that are generally taboo or uncomfortable. Identifying the function and impact of black humour is important given the prevalence of life-or-death situations, crucial clinical judgements and emotionally charged situations in the pre-hospital environment. The primary aim is to investigate the world of dark humour within the setting of experienced paramedics.

Dynamin independent endocytosis is an alternative cell entry mechanism for multiple animal viruses.

Mammalian receptor-mediated endocytosis (RME) often involves at least one of three isoforms of the large GTPase dynamin (Dyn). Dyn pinches-off vesicles at the plasma membrane and mediates uptake of many viruses, although some viruses directly penetrate the plasma membrane. RME is classically interrogated by genetic and pharmacological interference, but this has been hampered by undesired effects.

MECHANISMS OF TECOVIRIMAT ANTIVIRAL ACTIVITY AND POXVIRUS RESISTANCE.

Mpox is a zoonotic disease endemic in central and west Africa. However, since 2022, human-adapted mpox virus (MPXV) strains are causing large outbreaks spreading outside these regions, leading the World Health Organization to declare public health emergency twice. Tecovirimat, the most widely used drug to treat these infections, blocks viral egress through a poorly understood mechanism.

56Fe-ion Exposure Increases the Incidence of Lung and Brain Tumors at a Similar Rate in Male and Female Mice.

The main deterrent to long-term space travel is the risk of Radiation Exposure Induced Death (REID). The National Aeronautics and Space Administration (NASA) has adopted Permissible Exposure Levels (PELs) to limit the probability of REID to 3% for the risk of death due to radiation-induced carcinogenesis. The most significant contributor to current REID estimates for astronauts is the risk of lung cancer.

Energetics and Basic Stroke Kinematics of Swimming With Different Styles of Wetsuits.

Lim, B, Villalobos, A, Mercer, JA, and Crocker, GH. Energetics and basic stroke kinematics of swimming with different styles of wetsuits. J Strength Cond Res XX(X): 000-000, 2024-This study investigated the physiological responses and basic stroke kinematics while wearing different styles of wetsuits during submaximal intensity front-crawl swimming.