The loss of the urea cycle and ornithine metabolism in different insect orders: An omics approach.

Previous studies suggest that some insects require dietary arginine because they cannot synthesize this amino acid through the urea cycle. To determine whether this finding applies to all insects and what its metabolic implications are, we analysed the conservation of 20 genes involved in arginine biosynthesis and metabolism in the genomes of 150 species from 11 taxonomic orders. Our results showed that no insect can synthesize arginine via the urea cycle, as ornithine carbamoyltransferase is absent from all genomes analysed.

Intraoperative Effect of a Bilateral Ultrasound-Guided Quadratus Lumborum Block in Cats Undergoing Ovariectomy.

Objective: Investigate the effect of bilateral ultrasound-guided quadratus lumborum block (QLB) in the need for additional opioid administration in response to intraoperative nociception during ovariectomy in cats.

Methods: Thirty-six feral cats were randomly allocated to group control (C) or group QLB with 0.4 mL kg of 0.

Synchronous Intercostal Nerve Schwannomas: A Rare Cause of Chest Wall Pain.

Schwannomas are nerve sheath tumors arising from Schwann cells. Schwannomas of the intercostal nerve are extremely rare, with limited published literature. These tumors are generally regarded as benign asymptomatic.

Self-Efficacy and Self-Management in Musculoskeletal Rehabilitation: Strategies and Challenges Among Brazilian Physiotherapists.

Objectives: This study aimed to investigate the knowledge and strategies used by Brazilian physical therapists in assessing and promoting self-efficacy and self-management in musculoskeletal rehabilitation.

Methods: A nationwide cross-sectional online survey was conducted with licenced physical therapists recruited through professional networks and social media. The questionnaire, developed based on the CHERRIES checklist, assessed participants' knowledge, clinical strategies, and perceived barriers related to self-efficacy and self-management interventions.

Eradicating latent tuberculosis: use of interferon gamma release assay and isoniazid/rifapentine in people living with HIV/AIDS.

Tuberculosis (TB) is the most common comorbidity in people living with HIV/AIDS (PLWH), including those under antiretroviral treatment. PLWH are 28 times more likely to develop TB in Brazil, the leading cause of HIV-related deaths globally, with approximately 161,000 reported deaths worldwide in 2023. Early diagnosis of latent tuberculosis infection (LTBI) and prophylactic therapy can reduce TB cases, prevent disease progression, and decrease transmission in high-risk populations.