Nomogram based on a novel nutritional immune-inflammatory status score to predict postoperative outcomes in esophageal squamous cell carcinoma.

Background: The relationship between patient nutritional, immune, and inflammatory status is linked to tumor progression and prognosis. However, there are limited studies on the prognosis of esophageal squamous cell carcinoma (ESCC) after surgery based on the comprehensive indicators of these factors.

Aim: To develop and validate a novel nomogram based on a nutritional immune-inflammatory status (NIIS) score for predicting postoperative outcomes in ESCC.

Role of VDAC1 in hepatocyte apoptosis during acute liver injury in rats induced by obstructive jaundice.

Objectives: Exploring the role of VDAC1 in hepatocyte apoptosis during acute liver injury induced by obstructive jaundice.

Materials And Methods: Animal and cell models were established to investigate possible mechanisms during acute liver injury induced by OJ. Blood was collected for liver function assessment.

Ultra-small curcumin-ruthenium coordination polymer nanodots prevent renal ischemia-reperfusion injury and the progression to chronic kidney disease.

Renal ischemia-reperfusion (IR) induces tissue hypoxia, resulting in disrupted energy metabolism and heightened oxidative stress. These factors contribute to tubular cell damage, which is a leading cause of acute kidney injury (AKI) and can progress to chronic kidney disease (CKD). The excessive generation of reactive oxygen species (ROS) plays a crucial role in the pathogenesis of AKI.

Distinct role of primate DLPFC and LIP in hierarchical control of learned saccade sequences.

Learned action sequences are suggested to be organized hierarchically, but how the various hierarchical levels are processed by different cortical regions remains largely unknown. By training monkeys to perform heterogeneous saccade sequences, we investigated the role of the dorsolateral prefrontal cortex (DLPFC) and the lateral intraparietal cortex (LIP) in sequence planning and execution. The electrophysiological recording revealed that sequence-level initiation information was mostly signaled by DLPFC neurons, whereas subsequence-level transition was largely encoded by LIP neurons.

[Retracted] Paclitaxel induces apoptosis and reduces proliferation by targeting epidermal growth factor receptor signaling pathway in oral cavity squamous cell carcinoma.

[This retracts the article DOI: 10.3892/ol.2015.