Publications by authors named "J G Hindmarsh"
Article Synopsis
- The study aims to evaluate how diabetes treatment satisfaction varies by ethnicity among individuals with type 2 diabetes who have poor glycaemic control, highlighting a gap in current data about patient satisfaction in this context.
- A total of 346 participants took part in an 8-month clinical trial, completing the Diabetes Treatment Satisfaction Questionnaire (DTSQ) to assess their treatment satisfaction, which was found to be high overall.
- The results indicated that treatment satisfaction was especially high among Pacific peoples and older individuals, even though many participants had insufficient glucose-lowering therapy and suboptimal glycaemic control.
The fat mass and obesity associated (FTO) locus consistently associates with higher body mass index (BMI) across diverse ancestral groups. However, previous small studies of people of Polynesian ancestries have failed to replicate the association. In this study, we used Bayesian meta-analysis to test rs9939609, the most replicated FTO variant, for association with BMI with a large sample (n = 6095) of Aotearoa New Zealanders of Polynesian (Māori and Pacific) ancestry and of Samoan people living in the Independent State of Samoa and in American Samoa.
View Article and Find Full Text PDFBackground: Understanding which group of patients with type 2 diabetes will have the most glucose lowering response to certain medications (which target different aspects of glucose metabolism) is the first step in precision medicine.
Aims: We hypothesized that people with type 2 diabetes who generally have high insulin resistance, such as people of Māori/Pacific ethnicity, and those with obesity and/or hypertriglyceridemia (OHTG), would have greater glucose-lowering by pioglitazone (an insulin sensitizer) versus vildagliptin (an insulin secretagogue).
Methods: A randomised, open-label, two-period crossover trial was conducted in New Zealand.
Objectives: To assess the impact of an electronic prescribing template with decision support upon the frequency of prescription errors, guideline adherence (relating to dose ranges), and prescription legality when prescribing continuous subcutaneous infusions (CSCI) in a palliative demographic. Design, setting, and participants: Before-and-after study across a large UK city utilizing local prescribing data taken from patients receiving end-of-life care. Intervention: An electronic prescribing template with decision support.
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