Publications by authors named "J G Esposito"
Autism spectrum disorder (ASD) is a neurological disease and lifelong condition. The treatment gap in ASD has led to growing interest in alternative therapies, particularly in phytocannabinoids, which are naturally present in . Studies indicate that treatment with cannabidiol (CBD)-rich cannabis may possess the potential to improve fundamental ASD symptoms as well as comorbid symptoms.
View Article and Find Full Text PDFThe mouth and the oropharyngeal system are home to numerous bacterial species that constitute the so-called oral microbiome and play an important role for the integrity of the oral cavity, influencing the overall health of the body, as demonstrated by several studies. The aim of this study was to evaluate the bacterial modulation potential of a toothpaste (bioredoxin) containing curcumin and melatonin. Both substances have anti-inflammatory properties, as documented in several scientific reports.
View Article and Find Full Text PDFIn this work, toothpaste tube squeezability was tested by three different methods: assessment by a human panel, a tactile glove, and several purely instrumental tests. The panelists characterized squeezability in terms of the acceptability of the product. The tactile glove was utilized to determine the maximum grip forces (G) applied by the same panelists during their assessment.
View Article and Find Full Text PDFRacial and Ethnic Disparities in Predictive Accuracy of Machine Learning Algorithms Developed Using a National Database for 30-Day Complications Following Total Joint Arthroplasty.
J Arthroplasty
October 2024
Article Synopsis
- Machine learning (ML) algorithms have shown effectiveness in predicting complications after hip and knee surgeries, but their performance in racial and ethnic minorities has not been previously studied.
- This research analyzed data from over 267,000 patients to evaluate two ML models (histogram-based gradient boosting and random forest) in predicting 30-day complications among various racial and ethnic groups.
- The study found that while ML models performed well for the non-Hispanic White population, their predictive ability decreased significantly in racial and ethnic minority groups, especially among American-Indians, indicating potential disparities in healthcare outcomes.
There have been several methods established for immunohistochemical labeling of the PGP 9.5 antigen in human tissue for the assessment of epidermal nerve fiber density, none of which uses neutral-buffered formalin as the preferred fixative for paraffin-embedded tissue. The literature maintains that formalin-fixed paraffin embedded tissues are unable to be used for this purpose and that other fixatives must be used due to the cross-linkages caused by formalin fixation.
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