Publications by authors named "J G Cecatti"
Problem: COVID-19 during pregnancy is linked to increased maternal morbidity and a higher incidence of preterm births (PTBs), yet the underlying mechanisms remain unclear. Cellular senescence, characterized by the irreversible cessation of cell division, is a critical process in placental function, and its dysregulation has been implicated in pregnancy complications like PTB. Senescence can be induced by various stressors, including oxidative stress, DNA damage, and viral infections.
View Article and Find Full Text PDFArticle Synopsis
- Despite improvements in reducing maternal mortality worldwide, significant challenges remain, particularly in low- and middle-income countries.
- Effective strategies to lower maternal mortality need a combination of health policy implementation and social development.
- Primary care is crucial for recognizing risk factors and early signs of maternal health issues, while antenatal care addresses various conditions that can improve maternal outcomes.
Maternal immunization is a critical strategy to prevent both maternal and infant morbidity and mortality from several infectious diseases. When the first COVID-19 vaccines became available during the pandemic, there was mixed messaging and confusion amongst the broader public and among those associated with health care systems about the recommendations for COVID-19 vaccinations in pregnancy in many countries. A multi-country, mixed-methods study is being undertaken to describe how vaccine decision-making occurs amongst pregnant and postpartum women, with a focus on COVID-19 vaccines.
View Article and Find Full Text PDFPrevalence and management of ectopic and molar pregnancies in 17 countries in Africa and Latin America and the Caribbean: a secondary analysis of the WHO multi-country cross-sectional survey on abortion.
BMJ Open
October 2024
Article Synopsis
- The study investigates the prevalence, complications, and management of ectopic pregnancy (EP) and molar pregnancy (MP) in selected healthcare facilities across 17 countries in Africa and Latin America and the Caribbean (LAC).
- Data were collected from 280 healthcare facilities, revealing that 9.9% of women had EP or MP, with EP having more severe complications compared to MP.
- Findings suggest a need for improving quality care for EP and MP, emphasizing the importance of evidence-based management practices to reduce maternal morbidity and mortality in these regions.
Article Synopsis
- The goal of the study was to find out what people think are the important traits for research groups and how they can work well, especially in countries that don't have a lot of money.
- They talked to eleven people involved in these groups to see what everyone thought about the necessary qualities, like being committed and responsible.
- The study concluded that having dedicated leaders and members is more important for a network's success than having a lot of money, and support from institutions helps keep the network running.