Publications by authors named "J G Carvalheira"

Body composition abnormalities are prognostic markers in several types of cancer, including colorectal cancer (CRC). Using our data distribution on body composition assessments and classifications could improve clinical evaluations and support population-specific opportune interventions. This study aimed to evaluate the distribution of body composition from computed tomography and assess the associations with overall survival among patients with CRC.

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Trousseau Syndrome (TS) is defined as the occurrence of thromboembolic events prior to or simultaneously with the diagnosis of visceral neoplasia. In cases of multiple thromboembolisms, considering the possibility of TS, a screening for neoplasms may be warranted. We present a case study of a 61-year-old female who presented a neurological deficit.

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Background: Adipose tissue radiodensity and metabolic activity may influence COVID-19 outcomes. This study evaluated the association between adipose tissue characteristics and clinical outcomes in COVID-19 patients.

Methods: Two retrospective cohorts of hospitalized COVID-19 patients were analyzed.

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Background & Aims: The association of Prognostic Nutritional Index (PNI) with prognosis has been established for various cancer types, including rectal cancer. However, the precise relationship between PNI and body composition characteristics in patients with non-metastatic rectal cancer remain unclear. This study aimed to investigate the impact of PNI on overall survival and disease-free survival in non-metastatic rectal cancer patients undergoing total surgical resection.

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Article Synopsis
  • - The study investigates the fibrinolytic system in cancer patients, focusing on its role in tumor growth and mortality, using a fluorometric method to measure thrombin and plasmin generation in 323 cancer patients and 148 healthy controls.
  • - Results indicated that cancer patients showed a hypercoagulable profile, with alterations in thrombin production and increased plasmin generation, as 68 patients died during a 12-month follow-up.
  • - Two specific thrombin parameters, maximum amplitude and area under the curve, were linked to higher mortality risk in cancer patients, while no significant associations were found regarding plasmin generation.
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