Publications by authors named "J G Buchan"

Background: Understanding the financial and environmental impact of clinical pathways is important for designing sustainable services. This study aimed to compare the cost and carbon footprint of sub-Tenon's and topical anaesthesia for cataract surgery, benchmark minimum topical anaesthesia utilisation rates, and quantify the benefits of increased topical anaesthesia usage in the United Kingdom National Health Service (NHS).

Methods: The cost and carbon footprint of products and staffing for topical and sub-Tenon's anaesthesia for cataract surgery were calculated and applied to National Ophthalmology Database audit data.

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Purpose: Rapid genetic testing in the critical care setting may guide diagnostic evaluation, direct therapies, and help families and care providers make informed decisions about goals of care. We tested whether a simplified DNA extraction and library preparation process would enable us to perform ultra-rapid assessment of genetic risk for a Mendelian condition, based on information from an affected sibling, using long-read genome sequencing and targeted analysis.

Methods: Following extraction of DNA from cord blood and rapid library preparation, genome sequencing was performed on an Oxford Nanopore PromethION.

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Article Synopsis
  • A risk factor model was developed to predict the likelihood of posterior capsule rupture (PCR) during cataract surgery based on data from over 961,000 operations between 2016 and 2022 in the UK.
  • Key factors contributing to a higher risk of PCR included less experienced trainee surgeons, existing eye conditions like pseudoexfoliation, younger males, and advanced cataracts.
  • The model helps assess individual risks for patients and supports surgeons in adjusting their surgical strategies based on the complexity of cases to better manage PCR rates.
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