Publications by authors named "J G Bowen"
Background: In the DISCOMS (DISCOntinuation of disease-modifying therapies (DMTs) in multiple sclerosis (MS)) randomized clinical trial, we could not demonstrate that discontinuing MS DMTs in older, stable adults was not inferior to continuing DMTs. Relapses were rare in both groups, and most new disease activity was one to two new brain magnetic resonance imaging (MRI) lesions unassociated with clinical changes.
Objective/aims: Describe results of the DISCOMS extension study.
Article Synopsis
- Patchy data on litter decomposition in wetlands limits understanding of carbon storage, prompting a global study involving over 180 wetlands across multiple countries and climates.
- The study found that freshwater wetlands and tidal marshes had more organic matter remaining after decay, indicating better potential for carbon preservation in these areas.
- Elevated temperatures positively affect the decomposition of resistant organic matter, with projections suggesting an increase in decay rates by 2050; however, the impact varies by ecosystem type and highlights the need to recognize both local and global factors influencing carbon storage.
Objectives: Well-developed and finely tuned communication skills are foundational for pharmacists and should be at the core of Doctor of Pharmacy curricula. This narrative review aimed to identify and summarize useful instruments for pharmacy educators interested in assessing communication skills.
Findings: Fifty-seven studies were evaluated.
Tropical wetlands and freshwaters are major contributors to the growing atmospheric methane (CH) burden. Extensive peatland drainage has lowered CH emissions from peat soils in Southeast Asia, but the canals draining these peatlands may be hotspots of CH emissions. Alternatively, CH oxidation (consumption) by methanotrophic microorganisms may attenuate emissions.
View Article and Find Full Text PDFBackground: Fluoropyrimidine (FP) chemotherapies are commonly prescribed for upper and lower gastrointestinal, breast and head and neck malignancies. Over 16,000 people with cancer require FP chemotherapies per annum in Australia. Between 10 and 40% patients experience grade 3-4 (≥ G3) toxicities that require hospital-based management ± intensive care admission.
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