Nissen fundoplication in the management of gastroesophageal reflux occurring after repair of esophageal atresia.

Background/purpose: Gastroesophageal reflux is a major cause of complications after esophageal atresia repair. The suitability of the Nissen fundoplication in these patients is still disputed. Therefore, the authors evaluated the results of their prospective treatment protocol in those patients who underwent a Nissen fundoplication.

Gastroesophageal reflux and Barrett's esophagus in adults born with esophageal atresia.

Objective: Postoperative morbidity after correction of esophageal atresia is partly determined by gastroesophageal reflux disease, which has been proven to affect from one-half to two-thirds of patients during childhood. We conducted a follow-up study to test our hypothesis that, if former patients still show gastroesophageal reflux at adult age, they are at high risk for developing Barrett's esophagus, which is considered to be premalignant.

Methods: Of 69 patients born between 1971 and 1978, all having undergone a primary anastomosis, 24 had died, five of them because of aspiration.

Normal ranges of 24-hour pH-metry established in corrected esophageal atresia.

Background: This study was undertaken to determine baseline values of 24-hour pH-metry in children who had undergone correction for esophageal atresia.

Methods: A 24-hour pH-metry without medication was conducted in 13 patients with an uncomplicated postoperative course after correction of esophageal atresia. The pH-metry was performed in the hospital with a flexible glass electrode.

Prospective medical and surgical treatment of gastroesophageal reflux in esophageal atresia.

Background: Gastroesophageal reflux is a major cause of anastomotic complications after repair of esophageal atresia. For this reason, we evaluated a prospective, postoperative treatment protocol with the emphasis on comparing medical and operative treatment.

Study Design: From 1994 to 1995, 26 consecutive patients underwent correction of esophageal atresia in the Sophia Children's Hospital.

Function of pediatric Nissen-Rossetti fundoplication followed up into adolescence and adulthood.

Background: We analyzed the very long-term results of the Nissen-Rossetti fundoplication performed in young children. Little has been reported about follow-up longer than 5 years in homogeneous populations. This study concerns a homogeneous group with a minimum follow-up of 10 years; these former patients, therefore, are now adolescents or adults.