Publications by authors named "J Fujihara"
Article Synopsis
- - The study investigates how different essential element concentrations (Fe, Mg, Zn, Cu, Ca, P) in plasma could serve as potential markers for acute myocardial infarction (AMI) compared to other heart diseases like angina and heart failure.
- - Findings reveal that plasma levels of cardiac troponin T (TnT) are significantly higher in AMI patients and negatively correlated with copper (Cu) and calcium (Ca) concentrations.
- - While most element levels were within normal ranges, higher magnesium (Mg) levels and lower Cu and Ca levels in AMI patients may distinguish this condition from other heart diseases.
Thallium (Tl) is one of the most toxic metals and its historic use in homicides has led it to be known as "the poisoner's poison." This review summarizes the methods for identifying Tl and determining its concentrations in biological samples in recently reported poisoning cases, as well as the toxicokinetics, toxicological effects, toxicity mechanisms, and detoxication methods of Tl. Recent findings regarding Tl neurotoxicological pathways and toxicological effects of Tl during pregnancy are also presented.
View Article and Find Full Text PDFOur study was designed to examine the correlation between single nucleotide polymorphism (SNP) in the endoplasmic reticulum aminopeptidase 1 (ERAP1) gene, specifically focusing on rs27434, and plural tissue weight. We conducted this investigation using autopsy samples from the Japanese population. Blood samples were collected from 178 Japanese subjects who had undergone autopsies in Shimane Prefecture.
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- Cell-free DNA (cfDNA) is DNA found in blood that increases in concentration during certain diseases, including cancers like acute promyelocytic leukaemia (APL).
- In a study, researchers observed that cfDNA levels were slightly elevated in APL patients undergoing arsenic trioxide (ATO) treatment compared to healthy controls, with changes in cfDNA corresponding to plasma arsenic levels.
- The study reported specific fragment patterns of cfDNA in APL patients, suggesting that it might be released through necrosis or neutrophil extracellular traps, but more research is needed to determine if cfDNA can serve as a reliable biomarker for APL treatment effectiveness.
Peptides and nucleic acids with programmable sequences are widely explored for the production of tunable, self-assembling functional materials. Herein we demonstrate that the primary sequence of oligosaccharides can be designed to access materials with tunable shapes and properties. Synthetic cellulose-based oligomers were assembled into 2D or 3D rod-like crystallites.
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