Publications by authors named "J Fronek"
Skeletal Muscle P MR Spectroscopy Surpasses CT in Predicting Patient Survival After Liver Transplantation.
J Cachexia Sarcopenia Muscle
February 2025
Article Synopsis
- Patients with liver cirrhosis may face higher risks of severe outcomes after liver transplantation (LT) due to skeletal muscle changes, like sarcopenia and myosteatosis.
- A study analyzed 134 LT candidates, using CT scans and phantom MR spectroscopy (MRS) of calf muscles to assess muscle alterations and their effects on surgical outcomes and long-term survival.
- Results revealed that patients with abnormal MRS and CT-diagnosed myosteatosis had significantly worse long-term survival and higher surgical complications, indicating that these muscle changes can be critical indicators for post-transplant prognosis.
Background: Avulsion fractures of the sublime tubercle of the ulna are a cause of medial elbow pain and instability in overhead athletes.
Purpose: To compare outcomes after sublime tubercle avulsion fracture managed as a fracture (with cast immobilization) versus a soft tissue injury (without immobilization and with early range of motion [ROM]) to determine how to achieve the best outcomes for these injuries in adolescent throwing athletes.
Study Design: Cohort study; Level of evidence, 3.
On the basis of author's request the publisher of Physiological Research decided to change the license of the article to CC BY license.
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- A new study evaluated long-term outcomes of liver transplants from donors treated with hypothermic oxygenated machine perfusion (HOPE) across 22 European centers, involving 1,202 transplant cases from 2012 to 2021.
- The study showed high 1-, 3-, and 5-year death-censored graft survival rates for both donation after brain death (DBD) and donation after circulatory death (DCD), with low rates of primary non-function (PNF) and ischaemic cholangiopathy (IC).
- The findings indicate that HOPE treatment effectively improves liver transplant outcomes, regardless of the donor's risk profile, and supports its incorporation into routine clinical practice.
Background: Autologous vein grafts are widely used for bypass procedures in cardiovascular surgery. However, these grafts are susceptible to failure due to vein graft disease. Our study aimed to evaluate the impact of the latest-generation FRAME external support on vein graft remodeling in a preclinical model.
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