Publications by authors named "J Fraile"

Once present, peri-implantitis is difficult to fully eliminate. Surgical interventions show some promising results in fighting the disease, but for the time being, prevention remains the strongest tool.

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Cell therapy is a promising strategy for treating neurological pathologies but requires invasive methods to bypass the blood-brain barrier restrictions. The nose-to-brain route has been presented as a direct and less invasive alternative to access the brain. The primary limitations of this route are low retention in the olfactory epithelium and poor cell survival in the harsh conditions of the nasal cavity.

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Partially automated robotic systems, such as camera holders, represent a pivotal step towards enhancing efficiency and precision in surgical procedures. Therefore, this paper introduces an approach for real-time tool localization in laparoscopy surgery using convolutional neural networks. The proposed model, based on two Hourglass modules in series, can localize up to two surgical tools simultaneously.

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Article Synopsis
  • This study looked at how a protein called COX-2 affects liver damage caused by a condition called cholestasis, where bile can't flow properly.
  • Scientists used specially modified mice that always express COX-2 in their liver cells to see if it helps protect against liver injury.
  • The results showed that these COX-2 mice had less liver damage and inflammation, improved bile acid processing, and were better at handling stress in the liver compared to regular mice.
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Livestock monitoring is a task traditionally carried out through direct observation by experienced caretakers. By analyzing its behavior, it is possible to predict to a certain degree events that require human action, such as calving. However, this continuous monitoring is in many cases not feasible.

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