Publications by authors named "J Foronda"
Article Synopsis
- Coxsackievirus A6 (CVA6) has become the leading cause of hand, foot, and mouth disease (HFMD) outbreaks in multiple countries, including the Philippines, though local data on this serotype is scarce.
- From 2012 to 2017, researchers analyzed laboratory-confirmed CVA6 HFMD cases and found an increase in detection rates from 61.9% to 88.1%, primarily affecting young children, especially those from Luzon.
- Genetic analysis revealed the strains were predominantly of genotype D3b and RF-A group, emphasizing the need for continued viral surveillance to better understand HFMD in the Philippines.
Siglec-9 is an inhibitory receptor on human mast cells in vitro.
J Allergy Clin Immunol
September 2023
Background: Mast cell activation is critical for the development of allergic diseases. Ligation of sialic acid-binding immunoglobin-like lectins (Siglecs), such as Siglec-6, -7, and -8 as well as CD33, have been shown to inhibit mast cell activation. Recent studies showed that human mast cells express Siglec-9, an inhibitory receptor also expressed by neutrophils, monocytes, macrophages, and dendritic cells.
View Article and Find Full Text PDFMetal-oxide doped conductive polymers have been investigated as sensors in the field of gas-sensing. Recent developments have highlighted the role of intrinsically conductive polymers, that have reportedly offered high surface response towards the detection of volatile organic compounds (VOCs). In this work, we optimize the development of gas-sensors made of Polyaniline/Zinc oxide (PANI/ZnO) composite, capable of detecting a varied class of VOCs such as, ammonia, acetone, formaldehyde, methanol, and ethanol.
View Article and Find Full Text PDFObjective: Respiratory syncytial virus (RSV) is a leading cause of severe lower respiratory infection, and therefore, a major threat to global health. This study determined the epidemiological and molecular characteristics of RSV among cases of influenza-like illness (ILI) and severe acute respiratory infection (SARI) among children in the Philippines.
Method: The study included archived nasopharyngeal swab and oropharyngeal swab samples collected from patients under the age of five who are presented with ILI or SARI for the period of 2006-2016.
Objectives: Human adenoviruses (HAdV) are known to cause a wide range of diseases including acute respiratory infections, conjunctivitis, and acute gastroenteritis. In this study, we aimed to determine the serotypes of HAdV in patients with influenza-like illness (ILI) in the Philippines from 2006-2012 and to describe the demographic and epidemiological characteristics of patients who tested positive for HAdV.
Methods: Between 2006 and 2012, the Philippine National Influenza Centre detected HAdV in 1294 samples of patients with ILI.