Retrospective service evaluation of a specialist weaning unit.

Specialist weaning units (SWUs) aim to liberate patients with complex weaning failure from mechanical ventilation and facilitate their discharge from the ICU. This retrospective service evaluation reports the outcomes of a SWU at Wythenshawe Hospital, Manchester between 2017 and 2019. In total, 75.

TEMPERATURE AND SALINITY AFFECT DEVELOPMENT OF THE PARASITIC SEA ANEMONE EDWARDSIELLA LINEATA POTENTIALLY LIMITING ITS IMPACT AS A BIOLOGICAL CONTROL ON THE CTENOPHORE MNEMIOPSIS LEIDYI.

The lined sea anemone, Edwardsiella lineata, parasitizes the ctenophore Mnemiopsis leidyi, which is one of the most destructive marine invasive species in the world. Mnemiopsis leidyi is known to tolerate a wide range of environmental conditions. However, the environmental tolerances of its most prominent parasite have never been characterized.

Asthma and COPD as co-morbidities in patients hospitalised with Covid-19 disease: a global systematic review and meta-analysis.

Background: Factors predisposing to increased mortality with COVID-19 infection have been identified as male sex, hypertension, obesity, and increasing age. Early studies looking at airway diseases gave some contradictory results. The purpose of our study was to determine global variation in studies in patients hospitalized with COVID-19 in the prevalence of COPD and asthma; and to determine whether the presence of asthma or COPD affected mortality in the same hospital population.

Rampant asexual reproduction and limited dispersal in a mangrove population of the coral .

Corals are critical to marine biodiversity. Reproduction and dispersal are key to their resilience, but rarely quantified in nature. Exploiting a unique system-a fully censused, longitudinally characterized, semi-isolated population inhabiting mangroves-we used 2bRAD sequencing to demonstrate that rampant asexual reproduction most likely via parthenogenesis and limited dispersal enable the persistence of a natural population of thin-finger coral ().

Efficacy of antifibrotic drugs, nintedanib and pirfenidone, in treatment of progressive pulmonary fibrosis in both idiopathic pulmonary fibrosis (IPF) and non-IPF: a systematic review and meta-analysis.

Background: Research questions To compare the efficacy of nintedanib and pirfenidone in the treatment of progressive pulmonary fibrosis; and to compare the efficacy of anti-fibrotic therapy (grouping nintedanib and pirfenidone together) in patients with IPF versus patients with progressive lung fibrosis not classified as IPF.

Study Design And Methods: A search of databases including MEDLINE, EMBASE, PubMed, and clinicaltrials.gov was conducted.