Profileplasty: Comprehensive Facial Profile Management Algorithm Based on 426 Patients.

Objective: Profileplasty traditionally involves improving a nasal hump or an underprojected chin. However, this procedure can correct other facial defects like saddle nose or prognathism. To establish the best overall profile, the nose, the midface, and the chin should be considered altogether.

Sustainable assessment of ultrasound-assisted extraction of anthocyanins with bio-based solvents for upgrading grape pomace Cabernet Sauvignon derived from a winemaking process.

This work assessed the efficiency and sustainability of ultrasound-assisted extraction (UAE) of anthocyanins from grape pomace using bio-based solvents: Ethanol, Isopropanol, Propylene-glycol, and Ethylene-glycol at different concentrations (50 and 100 % v/v) and temperatures (25 °C and 50 °C). Higher ultrasonic intensities (UI) were obtained at 50 °C and 50 % v/v by decreasing solvents viscosities. Under these conditions, anthocyanin extractions were performed with different combinations of solvent to liquid ratio (SLR) at 1:10 and 1:50 g/mL, and UI (3.

Electrodialysis with Bipolar Membranes to valorise saline waste streams: Analysing the fate of valuable minor elements.

Brine mining can represent a valuable non-conventional resource for the extraction of Mg, Li, B, Sr and other Trace Elements (TEs) such as Rb, Cs, whose recoveries require chemical reagents such as alkaline and acidic solutions. In a circular strategy, these required chemicals can be produced in-situ through Electrodialysis with Bipolar Membranes (EDBM). In this work, a laboratory EDBM unit was operated using real brines from Trapani saltworks to investigate, for the first time, the migration of minor and trace ions, as Li, B, Sr, Cs and Rb through ion-exchange membranes (IEMs).

Synaptic Gα12/13 signaling establishes hippocampal PV inhibitory circuits.

Combinatorial networks of cell adhesion molecules and cell surface receptors drive fundamental aspects of neural circuit establishment and function. However, the intracellular signals orchestrated by these cell surface complexes remain less understood. Here, we report that the Gα12/13 pathway lies downstream of several GPCRs with critical synaptic functions.

Bentayga-I: Development of a Low-Cost and Open-Source Multispectral CubeSat for Marine Environment Monitoring and Prevention.

CubeSats have emerged as a promising alternative to satellite missions for studying remote areas where satellite data are scarce and insufficient, such as coastal and marine environments. However, their standard size and weight limitations make integrating remote sensing optical instruments challenging. This work presents the development of Bentayga-I, a CubeSat designed to validate PANDORA, a self-made, lightweight, cost-effective multispectral camera with interchangeable spectral optical filters, in near-space conditions.