Publications by authors named "J Fernandez Alen"
Objective: Spinal vertebral fractures pose a significant healthcare burden due to their frequency and impact on quality of life, resulting in substantial social costs. Minimally invasive surgery (MIS) offers advantages over traditional open surgery (OS), such as reduced tissue damage, less postoperative pain, and shorter hospital stays, although it involves higher implant costs. Research comparing the overall direct costs of these interventions is limited.
View Article and Find Full Text PDFBackground: Glioblastomas are among the most malignant tumors which, despite aggressive treatment, currently have an abysmal prognosis. These lesions are known to cause local and systemic perturbations in the coagulation system, leading to neoangiogenesis and a high risk of venous thromboembolism. Indeed, there have been multiple proposals of the coagulation system being a possible target for future treatment of these patients.
View Article and Find Full Text PDFArticle Synopsis
- * A study involving 71 patients revealed that those with aggressive WHO grade 2 meningiomas had higher glycated hemoglobin (HbA1c) levels than patients with benign grade 1 tumors.
- * The study found a notable percentage of patients were hyperglycemic, and older patients had higher HbA1c levels, indicating a possible link between age and glucose dysregulation in meningioma cases, highlighting the need for further research.
Background: Laryngoscopy and tracheal intubation lead to sympathetic stimulation resulting in hemodynamic fluctuations. We compared local anesthetic ropivacaine 0.75% with alpha agonist dexmedetomidine through ultrasonic nebulization for direct local action of the drug in the airway.
View Article and Find Full Text PDFBackground: Traumatic atlanto-occipital dislocation (AOD) is a life-threatening injury. Although traumatic brain injury (TBI) is associated with increased mortality in AOD patients, a detailed individual analysis of these patients is lacking in the literature.
Methods: Patients ≥16 years old who were diagnosed of AOD with concomitant severe TBI from 2010 to 2020 were included in this retrospective study.