[Preoperative preparation, antibiotic prophylaxis and surgical wound infection in breast surgery].

Introduction: The impact of surgical wound infection on public health justifies its surveillance and prevention. Our objectives were to estimate the incidence of surgical wound infection in breast procedures and assess its protocol of antibiotic prophylaxis and preoperative preparation.

Methods: Observational multicentre prospective cohort study of incidence of surgical wound infection.

Clinical outbreak of linezolid-resistant Staphylococcus aureus in an intensive care unit.

Context: Linezolid resistance is extremely uncommon in Staphylococcus aureus.

Objective: To report an outbreak with linezolid and methicillin-resistant S. aureus (LRSA) in an intensive care department and the effective control measures taken.

Resistance to linezolid is mediated by the cfr gene in the first report of an outbreak of linezolid-resistant Staphylococcus aureus.

Background: From April through June 2008, we identified 12 patients in the intensive care unit and 3 patients on other wards infected with methicillin-resistant Staphylococcus aureus that was also resistant to linezolid. We investigated the mechanism of resistance--point mutations in domain V of 23S ribosomal RNA (rRNA) or presence of the cfr gene--involved in the outbreak.

Methods: Strains for the study were obtained in the intensive care unit and other wards.

Epidemiology of biological-exposure incidents among Spanish healthcare workers.

Objective: To determine the frequency and the epidemiological characteristics of biological-exposure incidents occurring among healthcare personnel.

Design: Prospective surveillance study.

Setting: Participating Spanish primary-care and specialty centers from January 1994 to December 1997.

Influenza virus immunization effectivity in kidney transplant patients subjected to two different triple-drug therapy immunosuppression protocols: mycophenolate versus azathioprine.

Background: Due to possible complications and treatment limitations, the prevention of influenza in renal transplant (RT) patients is highly indicated.

Methods: Forty-nine patients with a 1-year functioning RT subjected to two different immunosuppressive regimens and 37 healthy relatives (HR) were administered the anti-influenza vaccine as recommended for 1996 to 1997. Anti-influenza antibody, creatinine, and immunological markers were estimated at 1 and 3 months after vaccination.