Publications by authors named "J Fearnley"
Article Synopsis
- Autophagy is a vital cellular process that helps maintain balance and remove damaged components, and its dysfunction is linked to diseases like cancer and metabolic syndromes.
- Studies suggest propolis, known for its antimicrobial and anti-inflammatory properties, may also influence autophagy, but this aspect hasn't been widely explored yet.
- This review aims to examine how propolis affects autophagy in biological models, which could lead to new propolis-based nutritional products and therapies.
The orange and cherry industries in New South Wales, Australia, are major horticulture industries with a high export value. Climate change has resulted in the carbon footprint of products being used by consumers to guide purchases meaning that products with a relatively high carbon footprint risk losing market access. The carbon footprint of cherry and orange production is unknown and there is no assessment of the success of climate change mitigation strategies to reduce the carbon footprint of their production and move production towards being carbon neutral.
View Article and Find Full Text PDFPropolis is a resin that is gathered by bees from exudates produced by various plants. Its exact chemical composition depends on the plants available near the hive. Bees use propolis to coat the surfaces of the hive, where it acts as an anti-infective.
View Article and Find Full Text PDFArticle Synopsis
- Propolis, a resinous substance collected by bees, has therapeutic uses in folk medicine and modern research highlights its potential as a bioactive component in biomaterials due to its antimicrobial, anti-inflammatory, and immune-modulating properties.
- Studies show that propolis generally enhances the antimicrobial properties and improves physicochemical characteristics of hydroxyapatite/calcium phosphate-based biomaterials, making it effective in wound healing without adversely affecting the materials.
- The effects of propolis on glass-based biomaterials can vary depending on its concentration, type of extract, and geographical source, potentially enhancing or harming mechanical properties, but consistently boosting antimicrobial and anti-inflammatory effects.
Profiling a propolis sample from Papua New Guinea (PNG) using high-resolution mass spectrometry indicated that it contained several triterpenoids. Further fractionation by column chromatography and medium-pressure liquid chromatography (MPLC) followed by nuclear magnetic resonance spectroscopy (NMR) identified 12 triterpenoids. Five of these were obtained pure and the others as mixtures of two or three compounds.
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