[Pigmented Paget's disease of the breast].

Introduction: Pigmented Paget's disease of the breast is an uncommon disease. Histology shows intraepidermal pagetoid cells positive for cytokeratin7. We report a difficult case with an atypical clinic presentation as a pigmented lesion and unusual immunohistochemical results such as absence of expression of cytokeratin7 (CK7).

QT dispersion in nonischemic dilated cardiomyopathy. A long-term evaluation.

Background: In idiopathic dilated cardiomyopathy (IDC), the predictive value of QT dispersion is still under debate.

Aims: This study assessed the role of QT dispersion for the long-term risk of cardiac death and of major arrhythmic events in IDC.

Methods And Results: In 162 patients with IDC (age 52+/-12 years), the QT interval on a 12-lead ECG was measured manually.

[Arrhythmias of primary hypertrophic cardiomyopathy].

Primary hypertrophic cardiomyopathy is a genetic disease causing sarcomere dysfunction. The structural and functional myocardial changes combine to produce cardiac arrhythmias related to reentry phenomena and to triggered automatic activity. The commonest arrhythmias are atrial fibrillation and ventricular arrhythmias; junctional tachycardias via the bundle of Kent are rare.

Segmental wall motion abnormalities in idiopathic dilated cardiomyopathy and their effect on prognosis.

There is considerable variability in segmental wall motion abnormalities and in the prognosis of idiopathic dilated cardiomyopathy (IDC). Radionuclide ventriculography with Fourier analysis was performed in 107 patients with angiographically proved IDC. Amplitude analysis located the wall motion abnormalities.