Publications by authors named "J Fairman"

Background: Recent articles have described the challenges in developing nurse leaders to advance nursing science, improve health, healthcare, and health equity, and build the next generation of nurses. Over the past 25 years, the Robert Wood Johnson Foundation (RWJF) has implemented many programs to develop nurse leaders to address these challenges.

Purpose: This article shares lessons learned from four RWJF programs and how the authors recommend those lessons can be applied today.

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Chlamydia trachomatis (Ct) is the most common bacterial sexually transmitted infection globally, and a vaccine is urgently needed to stop transmission and disease. Chlamydial Protease Activity Factor (CPAF) is an immunoprevalent and immunodominant antigen for CD4 T cells and B cells, which makes it a strong vaccine candidate. Due to the tolerogenic nature of the female genital tract (FGT) and its lack of secondary lymphoid tissue, effective induction of protective cell-mediated immunity will likely require potent and safe mucosal adjuvants.

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is ranked among the top five bacterial pathogens responsible for catheter-associated urinary tract infections, wound infections, secondary root canal infections, and infective endocarditis. Previously, we showed that inactivation of either the manganese- and iron-binding (EfaA) or zinc-binding (AdcA and AdcAII) lipoproteins significantly reduced virulence. Here, we explored whether immunization using a multi-valent approach induces protective immunity against systemic enterococcal infections.

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Article Synopsis
  • Chlamydia trachomatis (Ct) is the most prevalent bacterial STI worldwide, highlighting the urgent need for an effective vaccine.
  • The study focuses on Chlamydial Protease Activity Factor (CPAF), identified as a promising antigen for vaccine development due to its strong immune response in T and B cells.
  • Researchers tested different mucosal adjuvants, finding that intranasal vaccination with CPAF and a specific adjuvant (CDA) was safe and effective in reducing infection in mice, indicating potential for a new Chlamydia vaccine.
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There is increased national attention to the impact nurses can and should have in advancing health equity. Nurses of color have made important contributions in nursing and other sectors to this end, but their efforts remain invisible. To amplify the contribution of Latino nurses in advancing health equity, we use oral histories and supplemental records to examine the career of Henrietta Villaescusa, RN, FAAN to illuminate her impact across government, health, and nursing sectors in advocating for the health of Latino communities.

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