Apalutamide Prevents SARS-CoV-2 Infection in Lung Epithelial Cells and in Human Nasal Epithelial Cells.

In early 2020, the novel pathogenic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China, and rapidly propagated worldwide causing a global health emergency. SARS-CoV-2 binds to the angiotensin-converting enzyme 2 (ACE2) protein for cell entry, followed by proteolytic cleavage of the Spike (S) protein by the transmembrane serine protease 2 (TMPRSS2), allowing fusion of the viral and cellular membranes. Interestingly, TMPRSS2 is a key regulator in prostate cancer (PCa) progression which is regulated by androgen receptor (AR) signaling.

Data related to spectrum analyzes for phases identification, microstructure and mechanical properties of additive manufactured Ti6Al4V reinforced with nano Yttria stabilized zirconia.

Ti6Al4V reinforced by nano yttria-stabilized zirconia (nYSZ) addition parts were manufactured via selective laser additive manufacturing. A research paper entitled "Effect of nano-yttria stabilized zirconia addition on the microstructure and mechanical properties of Ti6Al4V parts manufactured by selective laser melting" [1] discuss the microstructure and mechanical properties relationships. This data paper presents the analytical elements used to perform Rietveld refinement using X-ray diffraction data (XRD) obtained on manufactured parts in order to uncover microstructure characteristics (phase, crystallographic texture, lattice parameters, crystallite size, etc.

XCT bone characterization of lattice structured implants fabricated by additive manufacturing.

Several cylindrical specimens and dental implants, presenting diagonal lattice structures with different cell sizes (600, 900 and 1200 μm) were additively manufactured by selective laser melting process. Then they were implanted for two months in a sheep. After removal, they were studied by Archimedes' method as well as X-ray computed tomography in order to assess the penetration of bone into the lattice.