Publications by authors named "J F Xian"
The diagnosis of occult hepatitis B virus (HBV) infection (OBI) is influenced by factors such as the lower limit of detection (LOD) of the HBV DNA test. However, in clinical practice and scientific research, the lower limit of quantification (LOQ) is often misused as the LOD. This study aims to investigate the impact of misuse of the LOD of the HBV DNA test on the detection rate of OBI, as well as the risk factors for OBI.
View Article and Find Full Text PDFBased on the target of carbon neutrality, it is very important to explore highly active and durable electrocatalysts for both the hydrogen evolution reaction (HER) and oxygen evolution reaction (OER). Herein, a series of NiFe-based metal-organic frameworks (MOFs) with the doping of various rare-earth elements (Ce, Y, and La) were grown on nickel foam by a facile solvothermal process. The representative CeNiFe-MOF showed amazing OER performance with ultralow overpotentials of 224 and 277 mV at 500 mA cm in 1.
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- Obesity is a growing global health issue, and while current pharmaceutical treatments exist, they often come with side effects.
- Natural compounds (phytoconstituents) show promise as safer and cost-effective alternatives, but their effectiveness is limited by challenges like poor solubility and low bioavailability.
- This study explores the categorization of phytoconstituents with anti-obesity properties, reviews the development of nano-drug delivery systems (NDDS) to improve their efficacy, and summarizes recent research to guide future obesity treatment strategies.
Article Synopsis
- The study focuses on cholera infections, specifically rare cases linked to hepatic space-occupying lesions, and highlights the effectiveness of metagenomic sequencing (mNGS) for accurate pathogen identification.
- A 75-year-old man experienced diarrhea and fever after eating crabs, leading to the discovery of a liver abscess, which was diagnosed as a non-O1/O139 cholera infection through mNGS and PCR.
- The case underscores the potential of mNGS to diagnose challenging infections that other traditional methods may miss, paving the way for better clinical outcomes.
Article Synopsis
- Type B lactic acidosis is a serious condition linked to certain cancers, particularly in blood-related cancers, and this case focuses on a 59-year-old woman with metastatic cervical neuroendocrine carcinoma who experienced severe symptoms and high lactate levels.
- Initial treatments like fluid replacement and sodium bicarbonate didn't work, leading to the administration of a lower dose of etoposide chemotherapy, which resulted in tumor lysis syndrome that was managed effectively.
- After chemotherapy, the patient's lactate levels dropped significantly, and her condition improved enough for her to be discharged, showcasing a potential treatment approach for malignancy-associated lactic acidosis and emphasizing the need for careful management of related complications.