Metabolomic Profiling of Disease Progression Following Radiotherapy for Breast Cancer.

Background: This study aims to explore metabolic biomarkers and pathways in breast cancer prognosis.

Methods: We performed a global post-radiotherapy (RT) urinary metabolomic analysis of 120 breast cancer patients: 60 progression-free (PF) patients as the reference and 60 with progressive disease (PD: recurrence, second primary, metastasis, or death). UPLC-MS/MS (Metabolon Inc.

SLowFlowS: A novel flow standard for semiconductor process gases.

Numerous process gases are used in the production of semiconductor chips. Accurate metering of these gases into process chambers is critical for maximizing device throughput and yield. A national flow standard for semiconductor process gases does not exist, forcing the industry to rely on approximate "meter factors" to extrapolate a meter calibration carried out with nitrogen to the actual process gas.

Locoregional Infusion of EGFR806-CAR T Cells for Recurrent or Refractory Pediatric CNS Tumors: Results of the Completed BrainChild02 Phase 1 Clinical Trial.

Background: Relapsed/refractory pediatric CNS tumors have a poor prognosis. EGFR is commonly overexpressed, but EGFRvIII mutations are uncommon. To target these tumors, we used chimeric antigen receptor (CAR) T cells with a binder based on mAb806 which recognizes ectopically expressed wild-type EGFR and EGFRvIII.

Long-term outcomes of the Universal 2 total wrist arthroplasty.

Aims: The Universal 2 total wrist arthroplasty (TWA) aims to alleviate wrist pain and restore function. This study investigates the survival time, revision rate, complication rate, and performs radiological analysis on Universal 2 TWAs in the long term.

Methods: Forty-seven Universal 2 TWA in 45 patients were performed between 2006 and 2014.