Results of a multidisciplinary strategy to improve the management of cardiovascular risk factors after liver transplantation.

Although liver transplantation (LT) recipients are at high cardiovascular risk (CVR), the management of CVR factors (CVRF) after LT is far from optimal and needs to be improved. For this reason, we developed a multidisciplinary protocol to standardize the identification, risk stratification, management, and targets of therapy of CVRF during the first post-LT year. The grade of identification and control of CVRF 12 months after LT in the postintervention cohort (LT January 2018-January 2020, n = 150) were compared with a control cohort who underwent LT between July 2015 and December 2016 (n = 100).

Increased cholesterol absorption rather than synthesis is involved in boosted protease inhibitor-associated hypercholesterolaemia.

Objective: The aim of this study was to compare the differential effects of first-line efavirenz (EFV)-based vs. boosted lopinavir-based antiretroviral regimens on cholesterol metabolism.

Design: Multicentre, open-label, randomized clinical trial.

Effects of dietary enrichment with conventional foods on energy and protein intake in older adults: a systematic review.

Context: Decreased food intake is a common problem among older adults; it is a known cause of weight loss and may lead to malnutrition.

Objective: The objective of this systematic review was to determine the effects of dietary enrichment with conventional foods on energy and protein intake in older adults.

Data Sources: Studies were identified through systematic searches of the following electronic databases: MEDLINE, via PubMed; CINAHL, via EBSCO; Web of Science; Scopus; and Google Scholar.

Effects of free leucine supplementation and resistance training on muscle strength and functional status in older adults: a randomized controlled trial.

Objective: To assess the effect of free leucine supplementation combined with resistance training versus resistance training only on muscle strength and functional status in older adults.

Methods: This was a randomized, double-blind, placebo-controlled, parallel study with two intervention groups. Thirty older adults were randomly assigned to receive either 10 g leucine/day (leucine group [LG], n=15) or a placebo (control group [CG], n=15), plus resistance training over a 12-week period.

Effects of ezetimibe on cholesterol metabolism in HIV-infected patients with protease inhibitor-associated dyslipidemia: a single-arm intervention trial.

Background: The effects of ezetimibe on cholesterol metabolism in HIV-infected patients receiving boosted protease inhibitors have not been thoroughly assessed. The aim of this study was to assess cholesterol homeostasis in patients with PI associated dyslipidemia and its relationship with the response to treatment with the cholesterol-absorption inhibitor ezetimibe.

Methods: Fifteen patients with ritonavir-boosted PI-containig therapy and LDL-cholesterol > 3.