[Cyto-histological correlation of malignant thyroid nodules: clinical factors as predictors of malignancy].

Introduction: Fine-needle aspiration (FNA) is routinely used to distinguish benign from malignant tumors in thyroid nodules. Most benign or malignant diagnosis are confirmed by histology, but for suspected malignancies (Follicular neoplasm and Hürthle-cell neoplasm histology is always required. Some clinical factors have been identified as predictors of malignancy in the suspicious cases with eventual interest for treatment options.

[Surgical treatment of primary hyperparathyroidism with intraoperative iPTH determination].

Introduction: Primary hyperparathyroidism (pHPT) is most frequently caused by a solitary adenoma. Surgical intervention has a high cure rate, particularly when associated with a fast intraoperative intact parathyroid hormone (IOPTH) assay.

Aim: to evaluate the performance and accuracy when applying this technique.

The impact of soccer training on the immune system.

Objective: The aim of this study was to evaluate whether the level of some immune markers changed in soccer players during pre-season and during playing-season.

Design: An observational study for one soccer season (one year).

Setting: Professional soccer players.

Cutaneous T-cell recruitment in toxic epidermal necrolysis. Further evidence of CD8+ lymphocyte involvement.

Background: Toxic epidermal necrolysis (TEN) is a life-threatening disease with severe mucocutaneous shedding. Although it is widely accepted that immune mechanisms are at play, the pathophysiology of TEN is still unknown. We studied the blister fluid inflammatory cells in three drug-related cases to further define the suspected T-cell involvement in TEN.

Circulating immune complexes in Buerger's disease. Endarteritis obliterans in young men.

Auto-antibodies such as anti-elastin, anti-collagen, anti-nuclear and anti-arterial, circulating immune complexes, and cellular responses to collagen I and III are known to be present in Buerger's disease (EO). Deposits of IgG, C3 and C4 have also been found in the vascular lesions of endarteritis obliterans (EO) in young men. The purpose of this study was to correlate clinical evidence of vascular disease with the presence of the circulating immune complexes.