Publications by authors named "J F Talbot"
Article Synopsis
- MASLD (formerly NAFLD) is a significant cause of liver disease and there are limited treatment options available to prevent liver fat accumulation.
- Research indicates that vasoactive intestinal peptide-producing neurons (VIP-neurons) impact fat absorption and IL-22 production, which may help protect the liver.
- In experiments on mice, decreased communication between VIP-neurons and type 3 innate lymphoid cells (ILC3) led to increased IL-22 production and reduced liver fat, suggesting this neuroimmune pathway could be a promising target for new therapies.
Article Synopsis
- Dopamine plays a crucial role in motivating individuals to exert effort for rewards, both for themselves and for others, as seen in studies involving Parkinson's Disease patients.
- While individuals generally show a greater willingness to exert effort for their own benefit, increasing dopamine availability through medication enhances prosocial motivation, leading patients to exert more effort for the benefit of others compared to when they are off medication.
- This research highlights the complex role of dopamine in shaping not only self-serving behaviors but also prosocial actions that are essential for social cohesion.
Introduction: Prostate cancer (PCa) is the most common cancer in men. Recurrence may occur in up to half of patients initially treated with curative intent for high-risk localised/locally advanced PCa. Pelvic nodal recurrence is common in this setting, but no clear standard of care exists for these patients, with potential therapeutic approaches including stereotactic body radiotherapy (SBRT) to the involved node(s) alone, extended nodal irradiation (ENI) to treat sites of potential micrometastatic spread in addition to involved node(s) and androgen deprivation therapy with or without additional systemic anticancer therapies.
View Article and Find Full Text PDFPsychophysiological indexes in the detection of deception: A systematic review.
Acta Psychol (Amst)
November 2024
Robust evidence on deception detection highlights that humans perform at chance level, especially when a truth-default cognitive threshold is crossed by the deceiver. This systematic review examined whether identification of deceptive stimuli elicits specific physiological responses in the detectors of deception. Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, five databases were searched for human studies that evaluate physiological reactivity to deceptive stimuli, along with behavioural responses.
View Article and Find Full Text PDFArticle Synopsis
- The study focuses on the behavior of nonspherical particles, particularly elongated ones, in shear flow, building on the historical work of Jeffery which described their motion.
- It employs Langevin simulations and the Fokker-Planck equation to analyze how these particles respond to noise and calculates key parameters that represent their ordering behaviors, such as nematic ordering and biaxiality.
- The research finds that as noise decreases or Péclet number increases, nematic order improves, while biaxiality peaks at a certain value, and it also reveals that particles in 3D rotate faster than in 2D under the same noise conditions.