Drug Development.

Background: Global epidemiological studies involving over nine million participants have shown a 35% lower incidence of Alzheimer's Disease (AD) in older cancer survivors compared to those without a history of cancer. This inverse relationship, consistent across recent studies with methodological controls, suggests that cancer itself, rather than cancer treatments, may offer protective factors against AD. This insight opens avenues for novel therapeutic strategies targeting early AD by harnessing cancer-associated protective factors.

Global Prevalence of Mental Health Problems Among Cancer Survivors: A Meta-Analysis From 31 Countries.

Background: With the improvement of medical treatment, the survival rate of cancer patients continues to rise; however, their psychological issues require further management. Currently, there is uncertainty regarding the prevalence of mental health problems among cancer survivors.

Objective: To quantitatively summarize the global prevalence of mental health problems in cancer survivors.

Preparation, characterization, stability and replenishing calcium ability of Moringa oleifera leaf peptide-calcium chelates.

Calcium deficiency has garnered significant attention as a global public health issue. A new generation of calcium supplements, peptide-calcium chelates, is expected to increase in market value. In this study, we produced MORP (MW < 1 kDa) from Moringa oleifera leaf protein via enzymatic hydrolysis for chelation with Ca to produce MORP-Ca.

Spin and valley dependent transport and tunneling magnetoresistance in irradiated ferromagnetic WSedouble barrier junctions.

Spin and valley polarizations (P and P) and tunneling magnetoresistance (TMR) are demonstrated in the ferromagnetic/barrier/normal/barrier/ferromagnetic WSe junction, with the gate voltage and off-resonant circularly polarized light (CPL) applied to the two barrier regions. The minimum incident energy of non-zero spin- and valley-resolved conductance has been derived, which is consistent with numerical calculations and depends on the electric potential U, CPL intensity ΔΩ, exchange field h, and magnetization configuration: parallel (P) or antiparallel (AP). For the P (AP) configuration, the energy region with P = -1 or P = 1 is wider (narrower) and increases with ΔΩ.