Cleavable side chain based conjugated polymers (CSCPs) represent a unique approach to offering solution processability with added benefits via the elimination of insulating side chains. This work highlights an optimally designed polythiophene-carboxylic acid based CSCP, POET-T2-COOH, which achieves a conductivity exceeding 350 S/cm in molecularly doped and side chain cleaved films, 100-100,000 times higher than three other structurally isomeric CSCPs. The high conductivity of POET-T2-COOH is accomplished via a new "cleavage with doping" methodology, synergistically combining a strong acid and a primary dopant.
View Article and Find Full Text PDFRev Sci Instrum
October 2024
The SPARC tokamak is a high-field, Bt0 ∼12 T, medium-sized, R0 = 1.85 m, tokamak that is presently under construction in Devens, MA, led by Commonwealth Fusion Systems. It will be used to de-risk the high-field tokamak path to a fusion power plant and demonstrate the commercial viability of fusion energy.
View Article and Find Full Text PDFBackground: Cardiovascular disease and cancer share a common risk factor: chronic stress/allostatic load (AL). A 1-point increase in AL is linked to up to a 30% higher risk of major cardiac events (MACE) in patients with prostate cancer. However, AL's role in MACE in breast cancer, lung cancer, or colorectal cancer remains unknown.
View Article and Find Full Text PDFBackground: The study determined the proportion of patients with pancreatic adenocarcinoma (PDAC) who had margin-positive disease and no other adverse pathologic findings (APF) using institutional and administrative datasets.
Methods: Patients with clinical stage I or II PDAC in the National Cancer Database (NCDB 2010-2020) and those who underwent pancreatectomy at the authors' institution (2010-2021) were identified. Isolated margin positivity (IMP) was defined as a positive surgical margin with no APF (negative nodes, no lymphovascular/perineural invasion).