Publications by authors named "J F Schwensen"
Contact allergy (CA) is a frequent condition in children; however, newer estimates of the prevalence of CA in children are lacking. Herein, we aim to provide an estimate of the prevalence of CA in children from 2010 to 2024. Two authors independently searched PubMed, Embase and Web of Science for studies reporting the prevalence of positive patch tests (PPTs) to allergens in populations including ≥ 100 children (< 18 years).
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- Rubber gloves often have rubber accelerators that can cause allergic reactions, but their specific content is not well understood.
- A study tested 51 gloves from various brands, finding that 90% of disposable gloves contained sensitizing rubber accelerators, particularly zinc dibutyldithiocarbamate (ZDBC) and zinc diethyldithiocarbamate (ZDEC).
- The research highlights the need for better labeling of rubber gloves, as even those claimed to be free of accelerators were found to have them, necessitating more transparency from manufacturers.
Article Synopsis
- Rubber accelerators like TETD and ZDEC, used in rubber vulcanization, can cause allergic reactions and may trigger cross-reactivity between each other.
- A study on mice showed that sensitization and subsequent exposure to either TETD or ZDEC resulted in increased skin irritation and immune cell proliferation.
- The findings indicate that individuals allergic to one compound may react to the other, suggesting such patients should avoid both substances to prevent allergic responses.
Hidden formaldehyde in cosmetic products.
Contact Dermatitis
December 2024
Background: Formaldehyde is a common cause of contact allergy. Hidden formaldehyde, that is, formaldehyde in products without formaldehyde releasers, has previously been detected in cosmetic products.
Objectives: The objective of this study was to investigate the content and causes of hidden formaldehyde in leave-on cosmetic products.
Article Synopsis
- Neomycin, an aminoglycoside antibiotic linked to contact allergies, was banned for human use in Denmark in October 2009 but is still present in certain vaccines.
- A study examining trends in neomycin contact allergies from 2000 to 2023 found an overall prevalence of 1.4%, with a notable decrease post-2009 (from 1.8% to 1.2%).
- The allergy was more common in individuals over 40 and those with facial dermatitis, but less common in those with occupational or hand dermatitis, indicating specific demographic and health associations without major changes over time.