Publications by authors named "J F Schved"
The question of whether scuba diving is safe for patients with a history of venous thromboembolism (VTE) remains unanswered. Cases of VTE have been reported after decompression accidents but not following properly conducted dives. However, the risk of VTE and bleeding on anticoagulant therapy during diving has yet to be defined.
View Article and Find Full Text PDFBackground: Any surgical procedure carries a risk for venous thromboembolism (VTE), albeit variable. Improvements in medical and surgical practices and the shortening of care pathways due to the development of day surgery and enhanced recovery after surgery, have reduced the perioperative risk for VTE.
Objective: A collaborative working group of experts in perioperative haemostasis updated in 2024 the recommendations for the Prevention of perioperative venous thromboembolism published in 2011.
Congenital fibrinogen deficiency (CFD) is a rare bleeding disorder caused by mutations in FGA, FGB, and FGG. We sought to comprehensively characterize patients with CFD using PRO-RBDD (Prospective Rare Bleeding Disorders Database). Clinical phenotypes, laboratory, and genetic features were investigated using retrospective data from the PRO-RBDD.
View Article and Find Full Text PDFSurgery in rare bleeding disorders: the prospective MARACHI study.
Res Pract Thromb Haemost
October 2023
Article Synopsis
- Bleeding risk assessment before surgery in patients with rare inherited bleeding disorders is complex, despite established bleeding scores and clotting factor measurements.
- A study involving 178 patients with low coagulation levels analyzed how hemostasis experts managed bleeding risks during 207 surgical procedures and the resulting bleeding outcomes.
- Results showed that most surgeries were performed without factor replacement, particularly in mild deficiencies, and indicated that factor levels and the type of surgery are more critical for deciding perioperative treatment than bleeding scores.
Article Synopsis
- Idiopathic purpura fulminans (IPF) is a serious coagulation disorder often linked to transient anti-protein S antibodies post-viral infection, especially after varicella, with additional complications potentially arising from anti-phospholipid antibodies and inherited thrombophilia.
- A study was conducted analyzing patients for inherited thrombophilia factors and anti-phospholipid antibodies (APL) across a French multicenter retrospective series, revealing that 28% of patients tested positive for inherited thrombophilia and 59% for APL.
- Despite the high prevalence of inherited thrombophilia and APL in patients with IPF, the study found no significant correlation between these factors and the risk of severe