Publications by authors named "J F Prinz"
Objective Of Surgery: The aim of endothermal pupilloplasty (EP) is to optimize centering of the pupil, contour, or size.
Indications: The EP is performed in patients with congenital or acquired corectopia or an irregular pupil shape. In individual cases the technique has also been used to tighten the iris in floppy iris syndrome and to adapt iris tissue edges in patients with sectoral iris defects or iridodialysis.
Factors influencing the outcomes of trabeculectomy, conventional canaloplasty, and mitomycin C augmented canaloplasty.
Graefes Arch Clin Exp Ophthalmol
October 2024
Purpose: To compare the efficacy, safety, and factors influencing the outcomes of trabeculectomy (TE), conventional canaloplasty (cCP), and mitomycin C augmented canaloplasty (mCP) in glaucoma patients.
Methods: Intraocular pressure (IOP), the number of IOP-lowering eye drops, and surgery-related complications were evaluated at baseline and through 18 months postoperatively. Correlations between patients' demographic data, ophthalmic and non-ophthalmic conditions, outcomes and complications were evaluated.
Purpose: To evaluate the treatment success and safety of ab interno canaloplasty (AbiC) combined with cataract surgery in glaucoma patients.
Methods: The prospective case study included 43 eyes that received an AbiC combined with cataract surgery (age 73.3 ± 8.
Article Synopsis
- The human IRGM gene is associated with inflammatory conditions like sepsis and Crohn's disease, where decreased expression can lead to increased inflammatory markers in the body.
- Prior research showed that changes in metabolism and mitochondrial functions are linked to increased inflammatory responses, but the exact mechanisms were unclear.
- New findings revealed that type I interferon (IFN) production in macrophages is crucial for heightened cytokine levels due to IRGM deficiency, and novel pathways affecting mitochondrial function contribute to this inflammatory response.
Article Synopsis
- The retina is part of the central nervous system and regrowing axons after injury is a challenge due to the lack of regenerative capabilities in its neurons.
- This study aimed to understand the molecular features of the retina under both neurodegenerative and regenerative conditions using a technique called Data-Independent Acquisition Mass Spectrometry to analyze proteins from different types of retinas.
- A total of 5,750 proteins were identified, revealing significant interactions with various signaling pathways and potential biomarkers that could aid neuro-regeneration, especially in conditions like glaucoma.