Publications by authors named "J F Plouffe"
Article Synopsis
- The study discusses the effective and selective synthesis of iminosugars, specifically 1,4-dideoxy-1,4-imino-D-arabinitol (DAB) and lentiginosine, focusing on their seven stereoisomers.
- The starting material for these syntheses is 4-benzoyl-6-deoxy-6-iodoglycopyranosides, yielding between 38% to 68% for DAB and between 44% to 89% for lentiginosine.
- A key highlight of the process is a complex multistep reaction involving zinc-mediated reductive elimination, reductive amination, and intramolecular nucleophilic substitution, which allows for the
Objective: To explore patient and family perspectives of a discharge bedside board for supporting engagement in patient care and discharge planning to inform tool revision.
Methods: This qualitative descriptive study included 45 semi-structured interviews with a purposeful sample of English-speaking patients ( = 44; mean age 58.5 years) and their family members ( = 5) across seven adult inpatient units at a tertiary acute care hospital in mid-western Canada.
While investigating aerobic anoxygenic phototrophs (AAP) from Lake Winnipeg's bacterial community, over 500 isolates were obtained. Relatives of 20 different species were examined simultaneously, identifying conditions for optimal growth or pigment production to determine features that may unify this group of phototrophs. All were distributed among assorted α-Proteobacterial families including Erythrobacteraceae, Sphingomonadaceae, Sphingosinicellaceae, Acetobacteraceae, Methylobacteriaceae, and Rhodobacteraceae.
View Article and Find Full Text PDFThe purpose of this study was to better understand the psychological momentum (PM) in varsity cross-country competitive runners during a 3000 m selection trials. A sequential explanatory mixed methods design was used: recruitment trial race day (quantitative) and interview day (qualitative + maximal aerobic running speed [MARS]). Sample was consisted of fifteen university distance runners ( = six women [25.
View Article and Find Full Text PDFPseudomonas chlororaphis PA23 is a biocontrol agent that, in addition to producing antifungal compounds, synthesizes polyhydroxyalkanoate (PHA) polymers as a carbon and energy sink. Quorum sensing (QS) and the anaerobic regulator (ANR) are required for PA23-mediated fungal suppression; however, the role of these regulators in PHA production is unknown. Strains lacking either QS or ANR accumulated less PHA polymers when propagated on Ramsay's minimal medium (RMM) with glucose or octanoate as the carbon source.
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