Multidisciplinary management of chronic refractory pain in autosomal dominant polycystic kidney disease.

Background: Chronic pain is often difficult to manage in autosomal dominant polycystic kidney disease (ADPKD) patients and sometimes even leads to nephrectomy. We analyzed the long-term efficacy of our innovative multidisciplinary protocol to treat chronic refractory pain that aims to preserve kidney function by applying among other sequential nerve blocks.

Methods: Patients were eligible if pain was present ≥3 months with a score of ≥50 on a visual analog scale (VAS) of 100, was negatively affecting quality of life and if there had been insufficient response to previous therapies, including opioid treatment.

Bacterial growth inhibition and short-term clinical efficacy of a vegetable oil-based mouthrinse: preliminary study.

Bacterial growth of a vegetable oil-based product was determined in vitro. Growth of Streptococcus mutans and Veillonella alcalescens was strongly inhibited for dilutions up to 50x. On the basis of these results, it was decided to evaluate the short-term, clinical efficacy of a 1:10 dilution of the concentrated product in water.

Sulcus temperature distributions in the absence and presence of oral hygiene.

In this study we investigated the possibility of using sulcus temperature measurements as an early indicator for the beginning of gingival inflammation. Sulcus temperature distributions over the arches appeared to obey a quadratic polynomial. With a test group of 10 volunteers, all dental students, small changes in temperature were measured after subjects refrained from all oral hygiene: A slight but significant tendency for the frontal temperature to increase after 14 days of no oral hygiene was, however, present.