Publications by authors named "J F Okulicz"

Objectives: Delays in HIV antiretroviral therapy (ART) have been associated with HIV disease progression and forward transmission. We evaluated the effectiveness of an accelerated ART virtual protocol (VP) for active duty (AD) members with incident HIV diagnosis.

Methods: Under the traditional protocol (TP), service members stationed worldwide were evaluated in-person at Brooke Army Medical Center (BAMC) and received comprehensive HIV care.

View Article and Find Full Text PDF

Introduction: Follow-up testing is recommended three months after patients initially test positive with Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (GC). Follow-up testing adherence in the United States has been reported below one third of women, even in universally insured populations. We assessed both the positivity of CT and GC infections in female basic military trainees and the rates of follow-up testing for those who tested positive.

View Article and Find Full Text PDF

Background: Treatment guidelines were developed early in the pandemic when much about COVID-19 was unknown. Given the evolution of SARS-CoV-2, real-world data can provide clinicians with updated information. The objective of this analysis was to assess mortality risk in patients hospitalized for COVID-19 during the Omicron period receiving remdesivir+dexamethasone versus dexamethasone alone.

View Article and Find Full Text PDF
Article Synopsis
  • Clinicians evaluate patient factors such as polypharmacy and comorbidities when prescribing treatments for COVID-19, particularly focusing on direct-acting antivirals (DAAs).
  • The study analyzed data from over 788,000 hospitalized COVID-19 patients to identify potential drug-drug interactions (DDIs) that could affect the use of DAAs like nirmatrelvir/ritonavir, remdesivir, and molnupiravir.
  • Findings revealed that a significant portion of patients (52%) received medications either contraindicated or to be avoided with nirmatrelvir/ritonavir, especially in older patients and those with higher comorbidity scores.
View Article and Find Full Text PDF