Publications by authors named "J F Nyland"

Article Synopsis
  • The study investigates the effectiveness of two types of bone grafts (packed cancellous vs. corticocancellous) used in repairing scaphoid waist nonunion fractures with volar locking plates.
  • Postoperative CT scans showed that 95% of patients achieved osseous bridging, but those with packed cancellous grafts had significantly better healing outcomes than those with corticocancellous grafts.
  • The findings suggest that using packed cancellous autografts may lead to faster and more effective bone healing in these cases.
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Background: Subacromial balloon spacer implantation (SBSI) attempts to decrease glenohumeral joint (GHJ) pain and improve function in patients with an irreparable rotator cuff tear (RCT) and minimal osteoarthritis. Between 12 and 26 weeks post-SBSI, gradual implant resorption may create a "balloon dip" that decreases GHJ function and increases pain. This retrospective cohort study attempted to delineate shoulder function, active mobility, strength, pain, and functional task impairment during the "balloon dip" period.

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Introduction: Opioid use during pregnancy and subsequent neonatal opioid withdrawal syndrome (NOWS) have been associated with poor developmental outcomes including cognitive functioning. Less is known about the underlying molecular effects of prenatal opioid exposure and subsequent withdrawal; however, given the recent increase in NOWS cases, there is a pressing need to better understand these effects, which may partially explain cognitive deficits that have been observed in both preclinical NOWS models and patients with NOWS. This study evaluated the effects of prenatal heroin exposure and subsequent precipitated withdrawal symptoms on microglial reactivity in the nucleus accumbens (NAc), dorsal hippocampus (HC), and ventral tegmental area (VTA) in rat neonates, as well as cognitive functioning at three developmental time points using the Morris Water Maze (MWM) task.

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Article Synopsis
  • Substance use disorder (SUD) and drug-related crime are rising in the U.S., and a program that helps people get treatment instead of being arrested could help reduce crime and overdose deaths.
  • The study looked at how a program that provides treatment to people caught doing low-level drug crimes affected their chances of getting arrested again, with three groups being compared: those who didn’t join, those who started but didn’t finish, and those who completed the program.
  • The results showed that people who completed the program were much less likely to get arrested again compared to those who didn’t engage or didn’t finish it.
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Article Synopsis
  • The study explores the use of glucagon-like peptide 1 receptor agonists (GLP-1RAs), specifically liraglutide, as a non-opioid treatment for opioid use disorder (OUD), addressing the high rates of relapse despite existing treatments.
  • It involves a randomized, double-blind, placebo-controlled clinical trial with 40 participants in residential treatment, assessing the medication's safety and effectiveness in reducing cravings through various measurements at different stages.
  • The findings aim to inform future research and improve strategies for treating OUD, potentially influencing healthcare practices and policies.
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