Publications by authors named "J F Ikoli"
Article Synopsis
- - The study investigates the relationship between age and sex and the thickness of the radial artery wall, using samples from 48 cadavers (30 men and 18 women).
- - Human radial arteries were prepared and measured to determine the intima-media thickness, with an average measurement taken across three sections of each artery.
- - Results indicate a significant correlation between radial artery wall thickness and age for both men and women, suggesting that these factors should be considered in assessments of arterial health.
Vedolizumab is a humanized monoclonal antibody that binds to the human a4β7 integrin and is approved for use in inflammatory bowel diseases. We describe a patient with severe, refractory erosive gingivostomatitis, which appeared a few days after the first dose of vedolizumab and resolved after discontinuation of the drug. We believe the gingivostomatitis to be a direct side effect of vedolizumab, rather than an extraintestinal manifestation of the underlying inflammatory bowel diseases.
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- - Primary cardiac B cell lymphoma is a rare condition, with fewer than 90 documented cases in medical literature, indicating its uncommon nature.
- - The case study highlights a 67-year-old woman with a long history of rheumatoid arthritis which led to the development of secondary Felty's syndrome, ultimately requiring hospitalization for abdominal pain.
- - Hospital investigations revealed a 5cm cardiac mass in the right atrium, and a biopsy confirmed the diagnosis of primary cardiac B cell lymphoma, suggesting a possible link to long-term treatment with TNFα antagonists like leflunomide and infliximab.
Background: We have been intrigued by the observation that aortic stenosis (AS) may be associated with characteristic features of mitral drug-induced valvular heart disease (DI-VHD) in patients exposed to valvulopathic drugs, thus suggesting that beyond restrictive heart valve regurgitation, valvulopathic drugs may be involved in the pathogenesis of AS.
Methods: Herein are reported echocardiographic features, and pathological findings encountered in a series of patients suffering from both AS (mean gradient >15mmHg) and mitral DI-VHD after valvulopathic drugs exposure. History of rheumatic fever, chest radiation therapy, systemic disease or bicuspid aortic valve disease were exclusion criteria.