Publications by authors named "J F Hasler"
Background: Little is known about the role that charitable copay assistance (CPA) plays in addressing access to care and financial distress. The study sought to evaluate financial distress and experience with CPA among patients with cancer and autoimmune disease.
Methods: This is a national cross-sectional self-administered anonymous electronic survey conducted among recipients of CPA to cover the costs of a drug for cancer or autoimmune disease.
Article Synopsis
- Sexual concerns are prevalent among breast cancer survivors, impacting their sexual adjustment significantly, which suggests that involving partners in the therapeutic process could be beneficial.
- The study tested the Intimacy Enhancement (IE) intervention, a telephone-based program for couples, to tackle these sexual issues, comparing its effectiveness to a control group intervention.
- Results indicated that the IE intervention led to notable short-term improvements in the sexual function and satisfaction of survivors, although sustaining these benefits over time may require additional strategies.
Background: Patients with rectal cancer staged as clinical T2N0 (cT2N0) are recommended to undergo upfront resection. However, when the tumor is subsequently upstaged to pathologic T3N0 (pT3N0), there are no clear guidelines for adjuvant treatment. This study aimed to analyze national trends in adjuvant management and to identify differences in morbidity or survival.
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- Neoadjuvant cisplatin-based chemotherapy (NAC) is typically given to patients with muscle-invasive bladder cancer (MIBC), but not all complete the planned cycles, leading to unclear prognoses for those receiving fewer than three cycles.
- A study analyzed outcomes in 256 patients with MIBC, revealing that those receiving <3 cycles had significantly lower rates of pathologic complete response (pCR), shorter recurrence-free survival (RFS) of 11.6 months, and a 5-year overall survival (OS) of only 13.3%, compared to those receiving ≥3 cycles.
- This research suggests that completing the full course of NAC is crucial for better patient outcomes, indicating a need for further studies to