Publications by authors named "J F HIRSCH"

Objective: This study aimed to compare physiological changes when wearing a N95 and surgical mask at rest.

Methods: 42 subjects aged 18-55 (19 males; age 22.98 ± 3.

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Article Synopsis
  • Caffeine, known for its effects on brain physiology as a neurostimulant, was studied for its impact on blood-brain barrier (BBB) permeability to water, using advanced imaging techniques.
  • Following caffeine consumption among ten healthy volunteers, cerebral blood flow (CBF) significantly decreased, while the exchange time (Tex)—a measure of BBB permeability—showed a non-significant declining trend.
  • The study suggests that the body's response to caffeine might involve increased water flux across the BBB, indicating a possible compensatory mechanism to preserve brain function.
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Purpose: Failure to rescue (FTR) is defined as mortality within 30 days following a major complication. While FTR has been studied in various brain tumor resections, its predictors in malignant brain tumor resection (mBTR) remain unexplored. This study aims to identify FTR predictors in mBTR resection patients using a frailty-driven model.

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Transcatheter aortic valve replacement (TAVR) has become a viable treatment option for patients with severe aortic stenosis among all risk subsets. As TAVR use becomes more prevalent and patients live longer with their transcatheter valve, an increasing number of these patients can be expected to present with ACS. Overall, there is a paucity of high-quality data detailing incidence, pathophysiology, and management of ACS in this subset.

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