Publications by authors named "J F Graveline"
Article Synopsis
- Current guidelines generally do not support the use of direct oral anticoagulants (DOACs) for treating cerebral venous thrombosis (CVT), even though they may offer advantages compared to standard therapies, prompting a systematic review of existing studies.
- The review analyzed 33 studies involving 279 patients treated with various DOACs, finding low rates of complications like new intracranial hemorrhage and recurrent CVT while reporting positive outcomes in terms of patient disability levels.
- Although the results indicate potential safety and efficacy of DOACs in CVT treatment, they also stress the need for more extensive and rigorous trials to confirm these findings and establish the best treatment practices.
We describe a case of a patient who presented with an acute stroke and thrombosed aneurysm of the same vessel. We review the literature on acute stroke management in the setting of an ischemic stroke caused by a thrombosed aneurysm, including intravenous thrombolysis and mechanical thrombectomy. We found that it is unclear whether thrombolysis is safe in these cases.
View Article and Find Full Text PDFBackground And Purpose: Cerebral venous thrombosis causes disability from venous infarct and hemorrhage and potential mortality. Anticoagulation improves survival and disability outcomes, yet direct oral anticoagulants are currently not indicated in cerebral venous thrombosis due to lack of evidence, despite being on the market for nearly a decade. This systematic review will collate evidence of reported safety and efficacy of direct oral anticoagulant therapy in cerebral venous thrombosis.
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