Publications by authors named "J F Fuzellier"
Background: Acute kidney injury (AKI) is associated with high case fatality in infective endocarditis (IE), but epidemiological data on the frequency of AKI during IE is scarce. We aimed to describe the frequency and risk factors for AKI during the course of IE using Kidney Disease: Improving Global Outcomes consensual criteria.
Methods: Using the French hospital discharge database (French acronym PMSI), we retrospectively reviewed the charts of 112 patients presenting with a first episode of probable or definite IE between January 2010 and May 2015.
Article Synopsis
- - The study aimed to assess changes in health-related quality of life (HRQOL) 6 months after elective cardiac surgery and identify predictors of poor HRQOL.
- - A total of 326 patients participated, with 26.6% showing a decline in physical HRQOL and 28.2% in mental HRQOL post-surgery; factors like acute renal failure and prolonged mechanical ventilation were linked to these declines.
- - Overall, while most patients experienced improved HRQOL after surgery, over a quarter faced deterioration, highlighting the need for clinicians to better inform patients about potential outcomes.
Background: High-dose heparin is used during cardiopulmonary bypass (CPB) to prevent thrombosis in the circuits used for extracorporeal circulation. The aim of this study was, initially, to develop a population pharmacokinetic/pharmacodynamic (PK/PD) model to assess the variability of PK/PD parameters and their correlation with the results of the routine haemostatic test activated clotting time (ACT) and thereafter to develop a Bayesian estimator enabling an individualized dosing strategy.
Methods: Fifty consecutive patients undergoing cardiac surgery with CPB were included in the study.
Article Synopsis
- The paper introduces an endoscopic expandable sizer designed for thoracoscopic aortic valve replacement using a sutureless prosthesis, allowing for dynamic sizing of the aortic annulus.
- In experiments with ten aortic torsos, the feasibility of the sizing tool was confirmed, and subsequent successful implantation of sutureless valves was achieved.
- The study concludes that the endoscopic expandable sizer is technically viable, with satisfactory valve size selection observed, although further testing with fluid dynamics is necessary before clinical trials.
Interest is growing in the clinical use of sutureless (SU) valves. However, indications in some anatomical sub-settings, like bicuspid aortic valves (BAV), have been so far limited. We discuss herein our initial experience with the implantation of the 3f Enable SU bioprosthesis in patients with a BAV.
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